A new STAT3 function: pH regulation
نویسندگان
چکیده
منابع مشابه
Regulation of hematopoietic cell development and function by Stat3.
Activation of the Jak/Stat pathway plays a central role in hematopoietic development. Here, we focus on unique functions for Stat3 in the development of the hematopoietic system. Recent studies highlight a critical role for Stat3 in the development of T helper cell and B cell subsets as well as dendritic cell development and maturation. Further, Stat3 appears to play an important function in li...
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UNLABELLED Recent proteomic data have uncovered an interdependence of PI3K and STAT3. In PI3K-tranformed murine cells, STAT3 is phosphorylated on Y705 and activated in a PI3K-dependent manner. Dominant negative STAT3 interferes with PI3K-induced oncogenic transformation. Phosphorylation of STAT3 in PI3K-transformed murine cells is mediated by the TEC kinase BMX. Observations on glioblastoma ste...
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Nutrigenomics is the study of the effect of nutrition on gene expression which discusses how DNA is converted to mRNA and then converted mRNA to protein, and is the basis for understanding the biological activity of edible compounds. Nutritional manipulations and nutritional approaches are key tools to influence the performance and health of organisms. Today, it has been shown that better nutri...
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ژورنال
عنوان ژورنال: Cell Research
سال: 2018
ISSN: 1001-0602,1748-7838
DOI: 10.1038/s41422-018-0098-3